Posts Tagged ‘Stem Cell Activation’

Growth Factors Are A Must For Stem Cell Activation

Wednesday, August 28th, 2013

A growth factor is a naturally occurring substance capable of stimulating cellular differentiation and proliferation.  In most cases, growth factors are a protein.  Growth factors and adult stem cells go hand in hand.

Once the growth factors bind to the cell-surface receptors a sequence of health promoting events inside the cell begin.  There are a number of different growth factors and they have different roles to perform.  However, to summarize their key role, once the cell communication and signaling is initiated, the growth factors get to work on facilitating their repair and renewal capabilities in a variety of ways ranging from tissue and wound repair, the healing of collagen, development of the central nervous system, and enhancing immune response and metabolic processes.

Here is just a snapshot of some important growth factors:

  • Epidermal growth factor (EGF)
  • Granulocyte colony-stimulating factor (G-CSF)
  • Fibroblast growth factor (FGF)
  • Insulin-like growth factor (IGF-1)
  • Insulin-like growth factor (IGF-2)
  • Nerve growth factor (NGF) and other neurotrophins
  • Platelet-derived growth factor (PDGF)
  • Transforming growth factor alpha(TGF-α)
  • Transforming growth factor beta(TGF-β)
  • Platelet-derived growth factor (PDGF)
  • IL-1- Cofactor for IL-3 and IL-6 [Activates T cells]
  • IL-6- Stimulates Ig synthesis [Growth factor for plasma cells]
  • Vascular endothelial growth factor (VEGF)

Here Doctor Hauser talks about the important role of growth factors.

Reversing Heart Failure With Stem Cells

Saturday, May 25th, 2013

(CNN) – Dr. Roberto Bolli’s face lights up when he talks about his true love: the human heart.

“The heart is really a miraculous organ. It beats 72 times a minute throughout our life, which means billions of times in our lifetime. And it never gets tired,” Bolli says.

Stem cells were taken from patients with severe heart failure and multiplied in a laboratory run by Dr. Piero Anversa at Brigham & Women’s Hospital in Boston. A few months later, each patient was re-infused with a million of his or her own stem cells.

The results were dramatic. Patients saw scar tissue replaced by working heart muscle and a significant improvement in their hearts’ ability to pump blood.  Dr. Bolli is hoping to start a larger trial by the fall of 2013.