Archive for September, 2012

Stem Cell Treatments Offer Huge Protential

Saturday, September 15th, 2012

Blogged by Stem Cell Worx. As reported in the Irish Medical Times.

Scientists at NUI Galway are investigating how adult stem cells might be used to develop new treatments for vascular disease, osteoarthritis and lung injury.

Stem cells hold great promise as an alternative to drugs and surgical procedures for treating a wide range of medical conditions including heart disease, arterial disease of the limbs, diabetes complications, arthritis and other inflammatory conditions, Prof Frank Barry said.

The University has become a leading centre of translational research in adult stem cells involving its National Centre for Biomedical Engineering Science (NCBES) and REMEDI.

A new Irish company Orbsen Therapeutics is developing proprietary technologies designed to isolate stem cells. Prof Barry is a Director of Orbsen Therapeutics. The NUI Galway spin-out is targeting the expanding regenerative medicine market. The treatment potential of stem cells is linked to their natural capacity to dampen inflammation and promote healing, repair and regeneration of damaged tissues.

According to Prof Barry: “Ireland has a strong research base in adult stem cell therapy and has the capacity for advanced stem cell bio-processing. There is huge potential in this market and we anticipate that there will be extraordinary growth over the next five-to-10 years. There are currently over 400 regenerative medicine products on the market with many more in development.” Orbsen Therapeutics has developed a clear pipeline of clinical indications which it hopes — using proprietary technologies — to bring through to clinical trial over the coming years. These include osteoarthritis, acute lung injury syndrome, diabetic foot ulcer, critical limb ischaemia and others. “Combining the utility, novelty and the value of its technologies, Orbsen is well-placed to take advantage of the many opportunities in this fast-moving and important emerging market”, said Brian Molloy, CEO of Orbsen Theraepeutics.

Adult Stem Cells from Blood to Cure Wrinkles

Wednesday, September 12th, 2012

GLASGOW, (LifeSiteNews.com) – British researchers announced this week that they may have discovered a cure for wrinkles using stem cells taken from a person’s blood. A Glasgow based biotechnology company, Pharmacells, has announced they will begin human clinical trials next year on a method of inducing stem cells taken from blood to replace the skin’s own cells as they break down during the aging process.

Blood derived stem cells

Blood derived stem cells
stemcellremedy.com

Athol Haas, the company’s chief executive, told British media, “The skin has a natural elastic property which comes from cells known as fibroblasts.

“The ability of the body to produce this elastic material slows down with age because the number of these fibroblasts decrease.

“By introducing large numbers of stem cells into the right place, we are increasing the ability of the body to produce this material. It is still in its early stages but we hope to begin phase one trials within the next 12 months.”

Pharmacells owns the patent on a method of harvesting, isolating and storing a newly discovered type of blood derived adult stem cell. The company says they have created a private stem cell bank, which people can use to store their cells “for future use in personalised medicine”.

“We also supply ‘our’ adult cell line into many types of research projects, allowing others access to one of the more significant stem cell lines available anywhere in the world.”

Older methods of obtaining stem cells from fat are not as successful, he said, being able to produce only five or ten million at a time. The company says that as many as 500 million stem cells can be obtained from only a small amount of normal blood, collected in the same way as any regular blood test.

“By introducing large numbers of stem cells into the right place, we are increasing the ability of the body to produce this natural material. It will be long lasting, we think at least five years if not longer,” Haas added.

Blood-derived, or haematopoietic stem cells are currently used in treatment of some cancers, and researchers are working towards using them to treat a variety of illnesses including leukemia and kidney diseases. Pharmacells hopes to use its method of extracting stem cells to work towards treatments for heart disease and osteoarthritis.